• Medications are the most common cause of SJS/TEN (typically within 1-3 weeks of taking the medication and could be a drug that is already discontinued).

• DRESS syndrome: facial erythema and swelling hallmark feature: unlike SJS culprit med can be longer duration of therapy (2 weeks to 2 months)

• Anti MDA-5 Dermato: ulcerated Gottron’s papules; painful palmar papules, pernio- like lesion on digits; poor prognosis-rapidly progressive interstitial lung disease

• PG: rapidly progressive, painful ulcer, prednisone responsive, exhibits pathergy