• Cumulative Life Course Impairment (CLCI) is when the physical, psychological, and social effects of psoriasis that occur over a lifetime potentially interfere with an individual's full potential.
  • In meta-analysis studies the IL-17s and IL-23s had the most efficacious treatment results in psoriasis.
  • Inverse/intertriginous psoriasis areas present with smooth, well-demarcated patches with erosions and maceration, and minimal scale.
  • Roflumilast is the only topical approved to treat inverse psoriasis.
  • For patients that have psoriasis on other parts of the body, a genital biopsy is not necessary for the diagnosis of genital disease.